There are only three people on Earth that have the capacity to really care about you. Parents, and if you have one, your spouse. Everyone else can act as angels for a time by giving support, comfort, and saying that they care. But, in the end, only a few will have the capacity to really care.
It's most unfortunate when you don't have parents on Earth who care and your spouse isn't there for you 110%. I believe there is no feeling worse than feeling alone.